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David
HOLMES Ph.D. Professor, Universidad de Santiago de Chile (www.usach.cl)
Professor David Holmes did his undergraduate work in Genetics
in Trinity College, Dublin, Ireland and obtained in Ph.D in
Molecular Biology from the California Institute of Technology.
He was a Damon Runyon Fellow in the Chemistry Dept. at Caltech
and then held various academic positions in universities in
the USA. He spent a few years working in the Research Laboratories
of General Electric. His research interests focus on bioinformatics and
genome biology especially related to microorganisms but also
with projects concerning the genomics of higher organisms
including Human. In 1993 he was awarded a Scientific Citation
Classic as one of the most referenced Biologists in the world.
He has
served on several national and international committees and
review boards including the National Science Foundation and
the WCPF Foundation. He is a member of the Editorial Board
of the J. of Industrial Microbiology and Biotechnology.
ACADEMIC
POSITIONS:
Several appointments in national and international institutions.
Undergraduate, Graduate and Post-Graduate teaching responsibilities
in Genetics, Molecular Biology, Bioinformatics and Genome
Biology. Currently Dr. Holmes is Full Professor and Director
of the Laboratory of Bioinformatics and Genome Biology at
the Universidad
de Santiago.
PUBLICATIONS:
Over
100 publications and 1 patent.
SELECTED
PUBLICATIONS:
Selkov, E., R. Overbeek, Y. Kogan, L. Chu,
V. Vonstein, D. HOLMES, S. Silver and M.
Fonstein. Functional Analysis of Gapped
Microbial Genomes: Principles with Examples
from Thiobacillus ferrooxidans. Proc.
Natl. Acad. Sci. U S A. 97: 3509- 3514 (2000).
HOLMES, D. S., Zhao, H-L, Levican,
G., Ratouchniak, J., Bonneyfoy, V., Varela, P., and Jedlicki
E. ISAfe1, an ISL3 Family Insertion Sequence
in Acidihiobacillus ferrooxidans. J. Bacteriol.
183: 4323-4329 (2001).
Levican, G., P. Bruscella, M. Guacucano,
C. Inostroza, V. Bonnefoy, D. S HOLMES and E. Jedlicki.
Characterization of the petC and resB Operons in Acidithiobacillus
ferrooxidans. J. Bacteriol. 184:
1498-1501 (2002).
Jose Luis Ramírez, Alicia González,
José María Cantú, Pamela Chavez-Crooker, Juan Carlos Leiva,
Jenny Blamey, Hernan Cortes and David HOLMES.
Latin-American Genome Initiative, the Creation
of a Network and Web-Based Resource to Aid and Nurture Genome
Biology in Developing Countries. Electronic Journal of Biotechnology
5, Dec 15, 2002 accessible at http://www.ejbiotechnology.info
Barreto, M., R. Quatrini, S. Bueno, C. Arriagada,
J. Valdes, S. Silver, E. Jedlicki and D. S. HOLMES.
Aspects of the Predicted Physiology of Acidithiobacillus
ferrooxidans Deduced from an Analysis of its Partial Genome
Sequence. (In press, Hydrometallurgy, 2003).
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