Untitled Document

Professor Mario Rosemblatt is a well-known Chilean immunologist. His most recent research attempts to ascertain how antigen presenting cells regulate lymphocyte homing by defining the combination of adhesion receptors on lymphocytes. Dr. Rosemblatt was appointment as Research Fellow in Medicine at Harvard University (1973) and Assistant Professor at Brown University. He was the first to publish a report on the use of monoclonal antibody technology to study muscle physiology, a manuscript that has earned more that 220 citations. In 1983, Dr. Rosemblatt returned to Chile and joined the Faculty of Sciences at the University of Chile where he founded one of the leading Chilean research groups in Immunology. He has been Invited Professor at the Faculty of Sciences, University of Paris and Investigator of the Association Against Cancer. Dr. Rosemblatt was Head Coordinator of the Cell Biology and Cell Physiology Study Section of Fondecyt, Chairman of the Biology Department at the Faculty of Sciences (University of Chile) and Head of the organizing committee and first Director for the career of Molecular Biotechnology at that Faculty. Dr. Rosemblatt has been advisor to several graduate and undergraduate students and is highly committed to the training of young immunologists.

ACADEMIC POSITIONS: Graduate teaching responsibilities in Immunology at the University of Chile, and Universidad Andrés Bello.

PUBLICATIONS: 41 original articles in refereed journals with more than 550 citations, 9 book chapters and monographs. 4 patents Co-editor of a Textbook in Immunology.

BONO, M.R., Reyes, L., ROSEMBLATT, M. (1999). A flow cytometric procedure for the quantification of cell adhesion in complex mixtures of cells. J. of Immunol Methods 223, 27-36.

Fierro, J.R. Mora, M.R. BONO, J. Morales, E. Buckel, D. Sauma and M. Rosemblatt. “Dendritic cells and the mode of action of anticalcineurinic drugs. An integrating hypothesis” In press, Nephrology Dialysis Transplantation. 2002.

D. Sauma, J.R. Mora, A. Fierro, J. Morales, C. Herzog, E. Buckel, M. Rosemblatt and M.R. Bono. “Low-dose prednisone accounts for the marked reduction on CD4+ and CD8+ T cells in renal transplant patients under triple therapy”. In press, Transplantation Proceedings, 2002.

L. I. Reyes, P. Escobar, M. R. Bono and M. Rosemblatt. “B lymphocyte adhesion to endothelial cells from human lymphoid tissue modulates tyrosine phosphorylation and endothelial cell activation”. In press, J. Immunol. 2002.

J.R. Mora, M.R. Bono, N. Manjunath, W. Weninger, M. Rosemblatt, U.H. von Andrian. "Peyer's patch dendritic cells provide tissue-specific instructions for effector T cell homing to the gut". Nature (In Press).